In course of a two-day conference organized by the US State Department and the Office of the NATO Secretary General they discussed the major challenges of current international relations and security, future of the Alliance, new challenges represented e.g. by new technologies and artificial intelligence, transatlantic relations, protection of critical infrastructure, Sahel or Iran. Part of the program was a discussion with three Assistant Secretaries General of NATO or meeting with the Secretary of State Mike Pompeo. The Czech Republic was represented by David Král, director of foreign policy analysis and planning department of the Ministry of Foreign Affairs of the Czech Republic.